Oxidative stress mediates an increased formation of vascular endothelial growth factor in human hepatocarcinoma cells exposed to erlotinib

The tyrosine kinase inhibitor erlotinib targets the receptor of epidermal growth factor (EGFR) involved in development of hepatocellular carcinoma (HCC). Although inefficient in established HCC, erlotinib has been recently proposed for HCC chemoprevention. Since Cyp3A4 and Cyp1A2 enzymes metabolize...

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Detalles Bibliográficos
Autores principales: Rohr-Udilova, Nataliya, Klinglmüller, Florian, Seif, Martha, Hayden, Hubert, Bilban, Martin, Pinter, Matthias, Stolze, Klaus, Sieghart, Wolfgang, Peck-Radosavljevic, Markus, Trauner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593629/
https://www.ncbi.nlm.nih.gov/pubmed/28915658
http://dx.doi.org/10.18632/oncotarget.19055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593629/
https://www.ncbi.nlm.nih.gov/pubmed/28915658
http://dx.doi.org/10.18632/oncotarget.19055

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