Integration of ALV into CTDSPL and CTDSPL2 genes in B-cell lymphomas promotes cell immortalization, migration and survival

Avian leukosis virus induces tumors in chickens by integrating into the genome and altering expression of nearby genes. Thus, ALV can be used as an insertional mutagenesis tool to identify novel genes involved in tumorigenesis. Deep sequencing analysis of viral integration sites has identified CTDSP...

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Detalles Bibliográficos
Autores principales: Winans, Shelby, Flynn, Alyssa, Malhotra, Sanandan, Balagopal, Vidya, Beemon, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593642/
https://www.ncbi.nlm.nih.gov/pubmed/28915671
http://dx.doi.org/10.18632/oncotarget.19328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593642/
https://www.ncbi.nlm.nih.gov/pubmed/28915671
http://dx.doi.org/10.18632/oncotarget.19328

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