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Evidence for biochemical barrier restoration: Topical solenopsin analogs improve inflammation and acanthosis in the KC-Tie2 mouse model of psoriasis
Psoriasis is a chronic inflammatory skin disease affecting 2.5–6 million patients in the United States. The cause of psoriasis remains unknown. Previous human and animal studies suggest that patients with a susceptible genetic background and some stimulus, such as barrier disruption, leads to a coor...
Autores principales: | Arbiser, Jack L., Nowak, Ron, Michaels, Kellie, Skabytska, Yuliya, Biedermann, Tilo, Lewis, Monica J., Bonner, Michael Y., Rao, Shikha, Gilbert, Linda C., Yusuf, Nabiha, Karlsson, Isabella, Fritz, Yi, Ward, Nicole L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593857/ https://www.ncbi.nlm.nih.gov/pubmed/28894119 http://dx.doi.org/10.1038/s41598-017-10580-y |
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