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Intrinsic property of phenylalanine to trigger protein aggregation and hemolysis has a direct relevance to phenylketonuria

Excess accumulation of phenylalanine is the characteristic of untreated Phenylketonuria (PKU), a well-known genetic abnormality, which triggers several neurological, physical and developmental severities. However, the fundamental mechanism behind the origin of such diverse health problems, particula...

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Detalles Bibliográficos
Autores principales: Anand, Bibin G., Dubey, Kriti, Shekhawat, Dolat S., Kar, Karunakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593866/
https://www.ncbi.nlm.nih.gov/pubmed/28894147
http://dx.doi.org/10.1038/s41598-017-10911-z