A pH-dependent Antibacterial Peptide Release Nano-system Blocks Tumor Growth in vivo without Toxicity

In this study, we designed a nano-system where a novel antibacterial peptide RGD-hylin a1 with reduced hemolysis than the commonly studied melittin was loaded onto mesoporous silica (HMS). We found out that the designed nano-system, RGD-hylin a1-HMS, released RGD-hylin a1 in a pH-dependent manner. I...

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Detalles Bibliográficos
Autores principales: Cao, Jing, Zhang, Yan, Shan, Yanke, Wang, Jingui, Liu, Fei, Liu, Hongrui, Xing, Gang, Lei, Jing, Zhou, Jiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593885/
https://www.ncbi.nlm.nih.gov/pubmed/28894233
http://dx.doi.org/10.1038/s41598-017-11687-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593885/
https://www.ncbi.nlm.nih.gov/pubmed/28894233
http://dx.doi.org/10.1038/s41598-017-11687-y

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