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Mechanical bone growth stimulation by magnetic fibre networks obtained through a competent finite element technique

Fibre networks combined with a matrix material in their void phase make the design of novel and smart composite materials possible. Their application is of great interest in the field of advanced paper or as bioactive tissue engineering scaffolds. In the present study, we analyse the mechanical inte...

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Autor principal: Bosbach, Wolfram A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593920/
https://www.ncbi.nlm.nih.gov/pubmed/28894138
http://dx.doi.org/10.1038/s41598-017-07731-6
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author Bosbach, Wolfram A.
author_facet Bosbach, Wolfram A.
author_sort Bosbach, Wolfram A.
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description Fibre networks combined with a matrix material in their void phase make the design of novel and smart composite materials possible. Their application is of great interest in the field of advanced paper or as bioactive tissue engineering scaffolds. In the present study, we analyse the mechanical interaction between metallic fibre networks under magnetic actuation and a matrix material. Experimentally validated FE models are combined for that purpose in one joint simulation. High performance computing facilities are used. The resulting strain in the composite’s matrix is not uniform across the sample volume. Instead we show that boundary conditions and proximity to the fibre structure strongly influence the local strain magnitude. An analytical model of local strain magnitude is derived. The strain magnitude of 0.001 which is of particular interest for bone growth stimulation is achievable by this assembly. In light of these findings, the investigated composite structure is suitable for creating and for regulating contactless a stress field which is to be imposed on the matrix material. Topics for future research will be the advanced modelling of the biological components and the potential medical utilisation.
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spelling pubmed-55939202017-09-13 Mechanical bone growth stimulation by magnetic fibre networks obtained through a competent finite element technique Bosbach, Wolfram A. Sci Rep Article Fibre networks combined with a matrix material in their void phase make the design of novel and smart composite materials possible. Their application is of great interest in the field of advanced paper or as bioactive tissue engineering scaffolds. In the present study, we analyse the mechanical interaction between metallic fibre networks under magnetic actuation and a matrix material. Experimentally validated FE models are combined for that purpose in one joint simulation. High performance computing facilities are used. The resulting strain in the composite’s matrix is not uniform across the sample volume. Instead we show that boundary conditions and proximity to the fibre structure strongly influence the local strain magnitude. An analytical model of local strain magnitude is derived. The strain magnitude of 0.001 which is of particular interest for bone growth stimulation is achievable by this assembly. In light of these findings, the investigated composite structure is suitable for creating and for regulating contactless a stress field which is to be imposed on the matrix material. Topics for future research will be the advanced modelling of the biological components and the potential medical utilisation. Nature Publishing Group UK 2017-09-11 /pmc/articles/PMC5593920/ /pubmed/28894138 http://dx.doi.org/10.1038/s41598-017-07731-6 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Bosbach, Wolfram A.
Mechanical bone growth stimulation by magnetic fibre networks obtained through a competent finite element technique
title Mechanical bone growth stimulation by magnetic fibre networks obtained through a competent finite element technique
title_full Mechanical bone growth stimulation by magnetic fibre networks obtained through a competent finite element technique
title_fullStr Mechanical bone growth stimulation by magnetic fibre networks obtained through a competent finite element technique
title_full_unstemmed Mechanical bone growth stimulation by magnetic fibre networks obtained through a competent finite element technique
title_short Mechanical bone growth stimulation by magnetic fibre networks obtained through a competent finite element technique
title_sort mechanical bone growth stimulation by magnetic fibre networks obtained through a competent finite element technique
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593920/
https://www.ncbi.nlm.nih.gov/pubmed/28894138
http://dx.doi.org/10.1038/s41598-017-07731-6
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