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Biophysical characterisation of the novel zinc binding property in Suppressor of Fused

Suppressor of Fused (SUFU) is a highly conserved protein that acts as a negative regulator of the Hedgehog (HH) signalling pathway, a major determinant of cell differentiation and proliferation. Therefore, SUFU deletion in mammals has devastating effects on embryo development. SUFU is part of a mult...

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Detalles Bibliográficos
Autores principales:	Jabrani, Amira, Makamte, Staëlle, Moreau, Emilie, Gharbi, Yasmine, Plessis, Anne, Bruzzone, Lucia, Sanial, Matthieu, Biou, Valérie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593987/ https://www.ncbi.nlm.nih.gov/pubmed/28894158 http://dx.doi.org/10.1038/s41598-017-11203-2

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