Correlation between ERG Fusion Protein and Androgen Receptor Expression by Immunohistochemistry in Prostate, Possible Role in Diagnosis and Therapy

Background: Recent discovery of gene rearrangements have brought a new look to the molecular pathogenesis of cancer. Gene fusions occur in nearly 60% of prostate adenocarcinoma, being the TMPRSS2-ERG one of the most common. Evidence supports the role of ERG fusion in tumorigenesis, progression and i...

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Detalles Bibliográficos
Autores principales: Navaei, Amir Hassan, Walter, Beatriz A, Moreno, Vanessa, Pack, Svetlana D, Pinto, Peter, Merino, Maria J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595090/
https://www.ncbi.nlm.nih.gov/pubmed/28900498
http://dx.doi.org/10.7150/jca.16751

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