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Epithelial expression and function of trypsin-3 in irritable bowel syndrome

OBJECTIVES: Proteases are key mediators of pain and altered enteric neuronal signalling, although the types and sources of these important intestinal mediators are unknown. We hypothesised that intestinal epithelium is a major source of trypsin-like activity in patients with IBS and this activity si...

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Detalles Bibliográficos
Autores principales: Rolland-Fourcade, Claire, Denadai-Souza, Alexandre, Cirillo, Carla, Lopez, Cintya, Jaramillo, Josue Obed, Desormeaux, Cleo, Cenac, Nicolas, Motta, Jean-Paul, Larauche, Muriel, Taché, Yvette, Berghe, Pieter Vanden, Neunlist, Michel, Coron, Emmanuel, Kirzin, Sylvain, Portier, Guillaume, Bonnet, Delphine, Alric, Laurent, Vanner, Stephen, Deraison, Celine, Vergnolle, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595105/
https://www.ncbi.nlm.nih.gov/pubmed/28096305
http://dx.doi.org/10.1136/gutjnl-2016-312094