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Iron Oxide Nanozyme: A Multifunctional Enzyme Mimetic for Biomedical Applications

Iron oxide nanoparticles have been widely used in many important fields due to their excellent nanoscale physical properties, such as magnetism/superparamagnetism. They are usually assumed to be biologically inert in biomedical applications. However, iron oxide nanoparticles were recently found to a...

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Detalles Bibliográficos
Autores principales: Gao, Lizeng, Fan, Kelong, Yan, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595127/
https://www.ncbi.nlm.nih.gov/pubmed/28900505
http://dx.doi.org/10.7150/thno.19738
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author Gao, Lizeng
Fan, Kelong
Yan, Xiyun
author_facet Gao, Lizeng
Fan, Kelong
Yan, Xiyun
author_sort Gao, Lizeng
collection PubMed
description Iron oxide nanoparticles have been widely used in many important fields due to their excellent nanoscale physical properties, such as magnetism/superparamagnetism. They are usually assumed to be biologically inert in biomedical applications. However, iron oxide nanoparticles were recently found to also possess intrinsic enzyme-like activities, and are now regarded as novel enzyme mimetics. A special term, “Nanozyme”, has thus been coined to highlight the intrinsic enzymatic properties of such nanomaterials. Since then, iron oxide nanoparticles have been used as nanozymes to facilitate biomedical applications. In this review, we will introduce the enzymatic features of iron oxide nanozyme (IONzyme), and summarize its novel applications in biomedicine.
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spelling pubmed-55951272017-09-12 Iron Oxide Nanozyme: A Multifunctional Enzyme Mimetic for Biomedical Applications Gao, Lizeng Fan, Kelong Yan, Xiyun Theranostics Review Iron oxide nanoparticles have been widely used in many important fields due to their excellent nanoscale physical properties, such as magnetism/superparamagnetism. They are usually assumed to be biologically inert in biomedical applications. However, iron oxide nanoparticles were recently found to also possess intrinsic enzyme-like activities, and are now regarded as novel enzyme mimetics. A special term, “Nanozyme”, has thus been coined to highlight the intrinsic enzymatic properties of such nanomaterials. Since then, iron oxide nanoparticles have been used as nanozymes to facilitate biomedical applications. In this review, we will introduce the enzymatic features of iron oxide nanozyme (IONzyme), and summarize its novel applications in biomedicine. Ivyspring International Publisher 2017-07-22 /pmc/articles/PMC5595127/ /pubmed/28900505 http://dx.doi.org/10.7150/thno.19738 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Gao, Lizeng
Fan, Kelong
Yan, Xiyun
Iron Oxide Nanozyme: A Multifunctional Enzyme Mimetic for Biomedical Applications
title Iron Oxide Nanozyme: A Multifunctional Enzyme Mimetic for Biomedical Applications
title_full Iron Oxide Nanozyme: A Multifunctional Enzyme Mimetic for Biomedical Applications
title_fullStr Iron Oxide Nanozyme: A Multifunctional Enzyme Mimetic for Biomedical Applications
title_full_unstemmed Iron Oxide Nanozyme: A Multifunctional Enzyme Mimetic for Biomedical Applications
title_short Iron Oxide Nanozyme: A Multifunctional Enzyme Mimetic for Biomedical Applications
title_sort iron oxide nanozyme: a multifunctional enzyme mimetic for biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595127/
https://www.ncbi.nlm.nih.gov/pubmed/28900505
http://dx.doi.org/10.7150/thno.19738
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