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Direct Macromolecular Drug Delivery to Cerebral Ischemia Area using Neutrophil-Mediated Nanoparticles
Delivery of macromolecular drugs to the brain is impeded by the blood brain barrier. The recruitment of leukocytes to lesions in the brain, a typical feature of neuroinflammation response which occurs in cerebral ischemia, offers a unique opportunity to deliver drugs to inflammation sites in the bra...
Autores principales: | Zhang, Chun, Ling, Cheng-li, Pang, Liang, Wang, Qi, Liu, Jing-xin, Wang, Bing-shan, Liang, Jian-ming, Guo, Yi-zhen, Qin, Jing, Wang, Jian-xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595130/ https://www.ncbi.nlm.nih.gov/pubmed/28900508 http://dx.doi.org/10.7150/thno.19979 |
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