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EGLN1/c-Myc Induced Lymphoid-Specific Helicase Inhibits Ferroptosis through Lipid Metabolic Gene Expression Changes

Ferroptosis is a newly discovered form of non-apoptotic cell death in multiple human diseases. However, the epigenetic mechanisms underlying ferroptosis remain poorly defined. First, we demonstrated that lymphoid-specific helicase (LSH), which is a DNA methylation modifier, interacted with WDR76 to...

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Detalles Bibliográficos
Autores principales: Jiang, Yiqun, Mao, Chao, Yang, Rui, Yan, Bin, Shi, Ying, Liu, Xiaoli, Lai, Weiwei, Liu, Yating, Wang, Xiang, Xiao, Desheng, Zhou, Hu, Cheng, Yan, Yu, Fenglei, Cao, Ya, Liu, Shuang, Yan, Qin, Tao, Yongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595132/
https://www.ncbi.nlm.nih.gov/pubmed/28900510
http://dx.doi.org/10.7150/thno.19988