A Nanosystem of Amphiphilic Oligopeptide-Drug Conjugate Actualizing Both αvβ3 Targeting and Reduction-Triggered Release for Maytansinoid

To design a prodrug-based self-assembling nanosystem with both ligand targeting and stimuli-responsive features, and elucidate the superiority of each targeting strategy and the synergistic effect between them, we synthesized four small molecule amphiphilic peptide-drug conjugates (APDCs) using mayt...

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Detalles Bibliográficos
Autores principales: Liang, Yanqin, Li, Suxin, Wang, Xiaoyou, He, Bo, He, Bing, Dai, Wenbing, Zhang, Hua, Wang, Xueqing, Wang, Yiguang, Zhou, Demin, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595133/
https://www.ncbi.nlm.nih.gov/pubmed/28900511
http://dx.doi.org/10.7150/thno.20242

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