Sensitive in vivo Visualization of Breast Cancer Using Ratiometric Protease-activatable Fluorescent Imaging Agent, AVB-620

With the goal of improving intraoperative cancer visualization, we have developed AVB-620, a novel intravenously administered, in vivo fluorescent peptide dye conjugate that highlights malignant tissue and is optimized for human use. Matrix metalloproteinases (MMPs) hydrolyze AVB-620 triggering tiss...

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Detalles Bibliográficos
Autores principales: Miampamba, Marcel, Liu, Junjie, Harootunian, Alec, Gale, Andrew J, Baird, Stephen, Chen, Steven L, Nguyen, Quyen T, Tsien, Roger Y, González, Jesús E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595138/
https://www.ncbi.nlm.nih.gov/pubmed/28900516
http://dx.doi.org/10.7150/thno.20678

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