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Sigma 1 receptor regulates ERK activation and promotes survival of optic nerve head astrocytes
The sigma 1 receptor (S1R) is a unique transmembrane protein that has been shown to regulate neuronal differentiation and cellular survival. It is expressed within several cell types throughout the nervous system and visceral organs, including neurons and glia within the eye. S1R ligands are therape...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595338/ https://www.ncbi.nlm.nih.gov/pubmed/28898265 http://dx.doi.org/10.1371/journal.pone.0184421 |