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Co-delivery of polyinosinic:polycytidylic acid and flagellin by poly(lactic-co-glycolic acid) MPs synergistically enhances immune response elicited by intranasally delivered hepatitis B surface antigen

The aim of the present work was to investigate the synergistic effect between toll-like receptor (TLR) 3 ligand polyinosinic:polycytidylic acid (pI:C) and TLR5 ligand flagellin (FLN) on immune responses induced by nasally delivered hepatitis B virus surface antigen (HBsAg). Mannan and chitosan oligo...

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Detalles Bibliográficos
Autores principales:	Dai, Xiaojing, He, Jintian, Zhang, Ruxia, Wu, Guanghao, Xiong, Fangfang, Zhao, Baohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595363/ https://www.ncbi.nlm.nih.gov/pubmed/28924346 http://dx.doi.org/10.2147/IJN.S146912

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