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Do you know this syndrome? Heerfordt-Waldenström syndrome

Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the anatomic pathology of affected organs. It is normall...

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Detalles Bibliográficos
Autores principales: Fraga, Rafael Cavanellas, Kakizaki, Priscila, Valente, Neusa Yuriko Sakai, Portocarrero, Larissa Karine Leite, Teixeira, Mônica Fernandes Senise, Senise, Priscilla Fernandes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595615/
https://www.ncbi.nlm.nih.gov/pubmed/28954117
http://dx.doi.org/10.1590/abd1806-4841.20175211
Descripción
Sumario:Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the anatomic pathology of affected organs. It is normally self-limiting, with cure achieved between 12 and 36 months, but some prolonged cases have been reported. Diagnosis of the syndrome is clinical, and treatment depends on the degree of systemic impairment. Oral corticosteroids represent the first line treatment option. The mortality rate ranges between 1 and 5% of cases.