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Do you know this syndrome? Heerfordt-Waldenström syndrome
Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the anatomic pathology of affected organs. It is normall...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Sociedade Brasileira de Dermatologia
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595615/ https://www.ncbi.nlm.nih.gov/pubmed/28954117 http://dx.doi.org/10.1590/abd1806-4841.20175211 |
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author | Fraga, Rafael Cavanellas Kakizaki, Priscila Valente, Neusa Yuriko Sakai Portocarrero, Larissa Karine Leite Teixeira, Mônica Fernandes Senise Senise, Priscilla Fernandes |
author_facet | Fraga, Rafael Cavanellas Kakizaki, Priscila Valente, Neusa Yuriko Sakai Portocarrero, Larissa Karine Leite Teixeira, Mônica Fernandes Senise Senise, Priscilla Fernandes |
author_sort | Fraga, Rafael Cavanellas |
collection | PubMed |
description | Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the anatomic pathology of affected organs. It is normally self-limiting, with cure achieved between 12 and 36 months, but some prolonged cases have been reported. Diagnosis of the syndrome is clinical, and treatment depends on the degree of systemic impairment. Oral corticosteroids represent the first line treatment option. The mortality rate ranges between 1 and 5% of cases. |
format | Online Article Text |
id | pubmed-5595615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-55956152017-09-19 Do you know this syndrome? Heerfordt-Waldenström syndrome Fraga, Rafael Cavanellas Kakizaki, Priscila Valente, Neusa Yuriko Sakai Portocarrero, Larissa Karine Leite Teixeira, Mônica Fernandes Senise Senise, Priscilla Fernandes An Bras Dermatol Syndrome in Question Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the anatomic pathology of affected organs. It is normally self-limiting, with cure achieved between 12 and 36 months, but some prolonged cases have been reported. Diagnosis of the syndrome is clinical, and treatment depends on the degree of systemic impairment. Oral corticosteroids represent the first line treatment option. The mortality rate ranges between 1 and 5% of cases. Sociedade Brasileira de Dermatologia 2017 /pmc/articles/PMC5595615/ /pubmed/28954117 http://dx.doi.org/10.1590/abd1806-4841.20175211 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way. |
spellingShingle | Syndrome in Question Fraga, Rafael Cavanellas Kakizaki, Priscila Valente, Neusa Yuriko Sakai Portocarrero, Larissa Karine Leite Teixeira, Mônica Fernandes Senise Senise, Priscilla Fernandes Do you know this syndrome? Heerfordt-Waldenström syndrome |
title | Do you know this syndrome? Heerfordt-Waldenström syndrome |
title_full | Do you know this syndrome? Heerfordt-Waldenström syndrome |
title_fullStr | Do you know this syndrome? Heerfordt-Waldenström syndrome |
title_full_unstemmed | Do you know this syndrome? Heerfordt-Waldenström syndrome |
title_short | Do you know this syndrome? Heerfordt-Waldenström syndrome |
title_sort | do you know this syndrome? heerfordt-waldenström syndrome |
topic | Syndrome in Question |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595615/ https://www.ncbi.nlm.nih.gov/pubmed/28954117 http://dx.doi.org/10.1590/abd1806-4841.20175211 |
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