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A light- and calcium-gated transcription factor for imaging and manipulating activated neurons
Activity remodels neurons, altering their molecular, structural, and electrical characteristics. To enable the selective characterization and manipulation of these neurons, we present FLARE, an engineered transcription factor that drives expression of fluorescent proteins, opsins, and other genetica...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595644/ https://www.ncbi.nlm.nih.gov/pubmed/28650461 http://dx.doi.org/10.1038/nbt.3909 |