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A light- and calcium-gated transcription factor for imaging and manipulating activated neurons

Activity remodels neurons, altering their molecular, structural, and electrical characteristics. To enable the selective characterization and manipulation of these neurons, we present FLARE, an engineered transcription factor that drives expression of fluorescent proteins, opsins, and other genetica...

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Detalles Bibliográficos
Autores principales: Wang, W., Wildes, C. P., Pattarabanjird, T., Sanchez, M. I., Glober, G.F., Matthews, G. A., Tye, K. M., Ting, A. Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595644/
https://www.ncbi.nlm.nih.gov/pubmed/28650461
http://dx.doi.org/10.1038/nbt.3909