Can FSH influence longevity?

It was recently reported that the extragonadal actions of follicle‐stimulating hormone (FSH) include regulation of brown and white adipose tissue function and thermogenesis. Based on these findings and on our evidence for reduced FSH levels and enhanced thermogenesis in long‐lived growth hormone (GH...

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Detalles Bibliográficos
Autor principal: Bartke, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595675/
https://www.ncbi.nlm.nih.gov/pubmed/28856803
http://dx.doi.org/10.1111/acel.12663
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author Bartke, Andrzej
author_facet Bartke, Andrzej
author_sort Bartke, Andrzej
collection PubMed
description It was recently reported that the extragonadal actions of follicle‐stimulating hormone (FSH) include regulation of brown and white adipose tissue function and thermogenesis. Based on these findings and on our evidence for reduced FSH levels and enhanced thermogenesis in long‐lived growth hormone (GH)‐deficient mice and GH‐resistant mice, we suggest that FSH may have a role in the control of aging and longevity. We speculate that alterations in FSH secretion may represent one of the mechanisms of trade‐offs between reproduction and aging.
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spelling pubmed-55956752017-10-01 Can FSH influence longevity? Bartke, Andrzej Aging Cell Commentaries It was recently reported that the extragonadal actions of follicle‐stimulating hormone (FSH) include regulation of brown and white adipose tissue function and thermogenesis. Based on these findings and on our evidence for reduced FSH levels and enhanced thermogenesis in long‐lived growth hormone (GH)‐deficient mice and GH‐resistant mice, we suggest that FSH may have a role in the control of aging and longevity. We speculate that alterations in FSH secretion may represent one of the mechanisms of trade‐offs between reproduction and aging. John Wiley and Sons Inc. 2017-08-30 2017-10 /pmc/articles/PMC5595675/ /pubmed/28856803 http://dx.doi.org/10.1111/acel.12663 Text en © 2017 The Author. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentaries
Bartke, Andrzej
Can FSH influence longevity?
title Can FSH influence longevity?
title_full Can FSH influence longevity?
title_fullStr Can FSH influence longevity?
title_full_unstemmed Can FSH influence longevity?
title_short Can FSH influence longevity?
title_sort can fsh influence longevity?
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595675/
https://www.ncbi.nlm.nih.gov/pubmed/28856803
http://dx.doi.org/10.1111/acel.12663
work_keys_str_mv AT bartkeandrzej canfshinfluencelongevity

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