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The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore
Excessive production of mitochondrial reactive oxygen species (mROS) is strongly associated with mitochondrial and cellular oxidative damage, aging, and degenerative diseases. However, mROS also induces pathways of protection of mitochondria that slow aging, inhibit cell death, and increase lifespan...
Autores principales: | Rottenberg, Hagai, Hoek, Jan B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595682/ https://www.ncbi.nlm.nih.gov/pubmed/28758328 http://dx.doi.org/10.1111/acel.12650 |
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