HDAC3 negatively regulates spatial memory in a mouse model of Alzheimer's disease

The accumulation and deposition of beta‐amyloid (Aβ) is a key neuropathological hallmark of Alzheimer's disease (AD). Histone deacetylases (HDACs) are promising therapeutic targets for the treatment of AD, while the specific HDAC isoforms associated with cognitive improvement are poorly underst...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaolei, Wang, Sulei, Yu, Linjie, Jin, Jiali, Ye, Xing, Liu, Yi, Xu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595690/
https://www.ncbi.nlm.nih.gov/pubmed/28771976
http://dx.doi.org/10.1111/acel.12642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595690/
https://www.ncbi.nlm.nih.gov/pubmed/28771976
http://dx.doi.org/10.1111/acel.12642

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