The SKN‐1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms

In C. elegans, the skn‐1 gene encodes a transcription factor that resembles mammalian Nrf2 and activates a detoxification response. skn‐1 promotes resistance to oxidative stress (Oxr) and also increases lifespan, and it has been suggested that the former causes the latter, consistent with the theory...

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Detalles Bibliográficos
Autores principales: Tullet, Jennifer M.A., Green, James W., Au, Catherine, Benedetto, Alexandre, Thompson, Maximillian A., Clark, Emily, Gilliat, Ann F., Young, Adelaide, Schmeisser, Kathrin, Gems, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Short Takes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595692/
https://www.ncbi.nlm.nih.gov/pubmed/28612944
http://dx.doi.org/10.1111/acel.12627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595692/
https://www.ncbi.nlm.nih.gov/pubmed/28612944
http://dx.doi.org/10.1111/acel.12627

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