The SKN‐1/Nrf2 transcription factor can protect against oxidative stress and increase lifespan in C. elegans by distinct mechanisms

In C. elegans, the skn‐1 gene encodes a transcription factor that resembles mammalian Nrf2 and activates a detoxification response. skn‐1 promotes resistance to oxidative stress (Oxr) and also increases lifespan, and it has been suggested that the former causes the latter, consistent with the theory...

Descripción completa

Detalles Bibliográficos
Autores principales: Tullet, Jennifer M.A., Green, James W., Au, Catherine, Benedetto, Alexandre, Thompson, Maximillian A., Clark, Emily, Gilliat, Ann F., Young, Adelaide, Schmeisser, Kathrin, Gems, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Short Takes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595692/
https://www.ncbi.nlm.nih.gov/pubmed/28612944
http://dx.doi.org/10.1111/acel.12627

Ejemplares similares

Ejemplares similares