Combined deficiency of the Cnr1 and Cnr2 receptors protects against age‐related bone loss by osteoclast inhibition

The endocannabinoid system plays a role in regulating bone mass and bone cell activity and inactivation of the type 1 (Cnr1) or type 2 (Cnr2) cannabinoid receptors influences peak bone mass and age‐related bone loss. As the Cnr1 and Cnr2 receptors have limited homology and are activated by different...

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Detalles Bibliográficos
Autores principales: Sophocleous, Antonia, Marino, Silvia, Kabir, Dilruba, Ralston, Stuart H., Idris, Aymen I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595693/
https://www.ncbi.nlm.nih.gov/pubmed/28752643
http://dx.doi.org/10.1111/acel.12638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595693/
https://www.ncbi.nlm.nih.gov/pubmed/28752643
http://dx.doi.org/10.1111/acel.12638

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