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Genetic Ablation of Fgf23 or Klotho Does not Modulate Experimental Heart Hypertrophy Induced by Pressure Overload

Left ventricular hypertrophy (LVH) ultimately leads to heart failure in conditions of increased cardiac pre- or afterload. The bone-derived phosphaturic and sodium-conserving hormone fibroblast growth factor-23 (FGF23) and its co-receptor Klotho have been implicated in the development of uremic LVH....

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Detalles Bibliográficos
Autores principales:	Slavic, Svetlana, Ford, Kristopher, Modert, Magalie, Becirovic, Amarela, Handschuh, Stephan, Baierl, Andreas, Katica, Nejla, Zeitz, Ute, Erben, Reinhold G., Andrukhova, Olena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595838/ https://www.ncbi.nlm.nih.gov/pubmed/28900153 http://dx.doi.org/10.1038/s41598-017-10140-4

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