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From malaria to cancer: Computational drug repositioning of amodiaquine using PLIP interaction patterns
Drug repositioning identifies new indications for known drugs. Here we report repositioning of the malaria drug amodiaquine as a potential anti-cancer agent. While most repositioning efforts emerge through serendipity, we have devised a computational approach, which exploits interaction patterns sha...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595859/ https://www.ncbi.nlm.nih.gov/pubmed/28900272 http://dx.doi.org/10.1038/s41598-017-11924-4 |