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Anti-Aβ single-chain variable fragment antibodies restore memory acquisition in a Drosophila model of Alzheimer’s disease

Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder triggered by the accumulation of soluble assemblies of the amyloid-β42 (Aβ42) peptide. Despite remarkable advances in understanding the pathogenesis of AD, the development of palliative therapies is still lacking. Engineered anti-Aβ4...

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Detalles Bibliográficos
Autores principales:	Martin-Peña, Alfonso, Rincon-Limas, Diego E., Fernandez-Funez, Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595865/ https://www.ncbi.nlm.nih.gov/pubmed/28900185 http://dx.doi.org/10.1038/s41598-017-11594-2

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