Genomic comparison of esophageal squamous cell carcinoma and its precursor lesions by multi-region whole-exome sequencing

Esophageal squamous dysplasia is believed to be the precursor lesion of esophageal squamous cell carcinoma (ESCC); however, the genetic evolution from dysplasia to ESCC remains poorly understood. Here, we applied multi-region whole-exome sequencing to samples from two cohorts, 45 ESCC patients with...

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Detalles Bibliográficos
Autores principales: Chen, Xi-Xi, Zhong, Qian, Liu, Yang, Yan, Shu-Mei, Chen, Zhang-Hua, Jin, Shan-Zhao, Xia, Tian-Liang, Li, Ruo-Yan, Zhou, Ai-Jun, Su, Zhe, Huang, Yu-Hua, Huang, Qi-Tao, Huang, Li-Yun, Zhang, Xing, Zhao, Yan-Na, Yun, Jin-Ping, Wu, Qiu-Liang, Lin, Dong-Xin, Bai, Fan, Zeng, Mu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595870/
https://www.ncbi.nlm.nih.gov/pubmed/28900112
http://dx.doi.org/10.1038/s41467-017-00650-0

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