Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium

It is unclear whether genetic markers interact with risk factors to influence atrial fibrillation (AF) risk. We performed genome-wide interaction analyses between genetic variants and age, sex, hypertension, and body mass index in the AFGen Consortium. Study-specific results were combined using meta...

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Detalles Bibliográficos
Autores principales: Weng, Lu-Chen, Lunetta, Kathryn L., Müller-Nurasyid, Martina, Smith, Albert Vernon, Thériault, Sébastien, Weeke, Peter E., Barnard, John, Bis, Joshua C., Lyytikäinen, Leo-Pekka, Kleber, Marcus E., Martinsson, Andreas, Lin, Henry J., Rienstra, Michiel, Trompet, Stella, Krijthe, Bouwe P., Dörr, Marcus, Klarin, Derek, Chasman, Daniel I., Sinner, Moritz F., Waldenberger, Melanie, Launer, Lenore J., Harris, Tamara B., Soliman, Elsayed Z., Alonso, Alvaro, Paré, Guillaume, Teixeira, Pedro L., Denny, Joshua C., Shoemaker, M. Benjamin, Van Wagoner, David R., Smith, Jonathan D., Psaty, Bruce M., Sotoodehnia, Nona, Taylor, Kent D., Kähönen, Mika, Nikus, Kjell, Delgado, Graciela E., Melander, Olle, Engström, Gunnar, Yao, Jie, Guo, Xiuqing, Christophersen, Ingrid E., Ellinor, Patrick T., Geelhoed, Bastiaan, Verweij, Niek, Macfarlane, Peter, Ford, Ian, Heeringa, Jan, Franco, Oscar H., Uitterlinden, André G., Völker, Uwe, Teumer, Alexander, Rose, Lynda M., Kääb, Stefan, Gudnason, Vilmundur, Arking, Dan E., Conen, David, Roden, Dan M., Chung, Mina K., Heckbert, Susan R., Benjamin, Emelia J., Lehtimäki, Terho, März, Winfried, Smith, J. Gustav, Rotter, Jerome I., van der Harst, Pim, Jukema, J. Wouter, Stricker, Bruno H., Felix, Stephan B., Albert, Christine M., Lubitz, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595875/
https://www.ncbi.nlm.nih.gov/pubmed/28900195
http://dx.doi.org/10.1038/s41598-017-09396-7

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