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Assessment of T-cell receptor repertoire and clonal expansion in peripheral T-cell lymphoma using RNA-seq data

T-cell clonality of peripheral T-cell lymphoma (PTCL) is routinely evaluated with a PCR-based method using genomic DNA. However, there are limitations with this approach. The purpose of this study was to determine the utility of RNA-seq for assessing T-cell clonality and T-cell antigen receptor (TCR...

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Detalles Bibliográficos
Autores principales:	Gong, Qiang, Wang, Chao, Zhang, Weiwei, Iqbal, Javeed, Hu, Yang, Greiner, Timothy C., Cornish, Adam, Kim, Jo-Heon, Rabadan, Raul, Abate, Francesco, Wang, Xin, Inghirami, Giorgio G., McKeithan, Timothy W., Chan, Wing C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595876/ https://www.ncbi.nlm.nih.gov/pubmed/28900149 http://dx.doi.org/10.1038/s41598-017-11310-0

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