Using CRISPR/Cas9-mediated gene editing to further explore growth and trade-off effects in myostatin-mutated F4 medaka (Oryzias latipes)

Myostatin (MSTN) suppresses skeletal muscle development and growth in mammals, but its role in fish is less well understood. Here we used CRISPR/Cas9 to mutate the MSTN gene in medaka (Oryzias latipes) and evaluate subsequent growth performance. We produced mutant F0 fish that carried different fram...

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Detalles Bibliográficos
Autores principales: Yeh, Ying-Chun, Kinoshita, Masato, Ng, Tze Hann, Chang, Yu-Hsuan, Maekawa, Shun, Chiang, Yi-An, Aoki, Takashi, Wang, Han-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595883/
https://www.ncbi.nlm.nih.gov/pubmed/28900124
http://dx.doi.org/10.1038/s41598-017-09966-9

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