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Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential

Discovery of first-in-class medicines for treating cancer is limited by concerns with their toxicity and safety profiles, while repurposing known drugs for new anticancer indications has become a viable alternative. Here, we have developed a new approach that utilizes cell cycle arresting patterns a...

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Detalles Bibliográficos
Autores principales:	Lo, Yu-Chen, Senese, Silvia, France, Bryan, Gholkar, Ankur A., Damoiseaux, Robert, Torres, Jorge Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595967/ https://www.ncbi.nlm.nih.gov/pubmed/28900159 http://dx.doi.org/10.1038/s41598-017-11508-2

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