A multiplex preclinical model for adenoid cystic carcinoma of the salivary gland identifies regorafenib as a potential therapeutic drug

Adenoid cystic carcinomas (ACC) are rare salivary gland cancers with a high incidence of metastases. In order to study this tumor type, a reliable model system exhibiting the molecular features of this tumor is critical, but none exists, thereby inhibiting in-vitro studies and the analysis of metast...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Choudhury, Sujata, Wangsa, Darawalee, Lescott, Chamille J., Wilkins, Devan J., Sripadhan, Praathibha, Liu, Xuefeng, Wangsa, Danny, Ried, Thomas, Moskaluk, Christopher, Wick, Michael J., Glasgow, Eric, Schlegel, Richard, Agarwal, Seema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595986/
https://www.ncbi.nlm.nih.gov/pubmed/28900283
http://dx.doi.org/10.1038/s41598-017-11764-2

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