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The L-type Voltage-Gated Calcium Channel co-localizes with Syntaxin 1A in nano-clusters at the plasma membrane
The secretory signal elicited by membrane depolarization traverses from the Ca(2+)-bound α(1)1.2 pore-forming subunit of the L-type Ca(2+)-channel (Cav1.2) to syntaxin 1 A (Sx1A) via an intra-membrane signaling mechanism. Here, we report the use of two-color Photo-Activated-Localization-Microscopy (...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595989/ https://www.ncbi.nlm.nih.gov/pubmed/28900128 http://dx.doi.org/10.1038/s41598-017-10588-4 |