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A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating

A microfluidic chip with a controllable and integrated piezoelectric pump was proposed and demonstrated, where the pump was designed as a micro-actuator based on polyvinylidene fluoride (PVDF) organic piezoelectric film. In this case, the pump should integrate with the microfluidics device very well...

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Autores principales: Zhao, Bei, Cui, Xingye, Ren, Wei, Xu, Feng, Liu, Ming, Ye, Zuo-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596006/
https://www.ncbi.nlm.nih.gov/pubmed/28900226
http://dx.doi.org/10.1038/s41598-017-10785-1
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author Zhao, Bei
Cui, Xingye
Ren, Wei
Xu, Feng
Liu, Ming
Ye, Zuo-Guang
author_facet Zhao, Bei
Cui, Xingye
Ren, Wei
Xu, Feng
Liu, Ming
Ye, Zuo-Guang
author_sort Zhao, Bei
collection PubMed
description A microfluidic chip with a controllable and integrated piezoelectric pump was proposed and demonstrated, where the pump was designed as a micro-actuator based on polyvinylidene fluoride (PVDF) organic piezoelectric film. In this case, the pump should integrate with the microfluidics device very well into one chip. The flow rate can be precisely controlled in the range of 0–300 µl/min for water by tuning the V(pp) and frequency of Alternating Current (AC) voltage applied on the diaphragm. To analyze the relationship between the flow rate and the deflection of diaphragm, the deformations of diaphragm at different voltages were researched. The displacement of diaphragm was defined as 17.2 µm at the voltages of 3.5 kV, 5 Hz when the pump chamber was full of water. We have used the integrated microfluidic chip with two pumps for droplet generation to demonstrate its great potential for application in droplet-based microfluidic chip.
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spelling pubmed-55960062017-09-15 A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating Zhao, Bei Cui, Xingye Ren, Wei Xu, Feng Liu, Ming Ye, Zuo-Guang Sci Rep Article A microfluidic chip with a controllable and integrated piezoelectric pump was proposed and demonstrated, where the pump was designed as a micro-actuator based on polyvinylidene fluoride (PVDF) organic piezoelectric film. In this case, the pump should integrate with the microfluidics device very well into one chip. The flow rate can be precisely controlled in the range of 0–300 µl/min for water by tuning the V(pp) and frequency of Alternating Current (AC) voltage applied on the diaphragm. To analyze the relationship between the flow rate and the deflection of diaphragm, the deformations of diaphragm at different voltages were researched. The displacement of diaphragm was defined as 17.2 µm at the voltages of 3.5 kV, 5 Hz when the pump chamber was full of water. We have used the integrated microfluidic chip with two pumps for droplet generation to demonstrate its great potential for application in droplet-based microfluidic chip. Nature Publishing Group UK 2017-09-12 /pmc/articles/PMC5596006/ /pubmed/28900226 http://dx.doi.org/10.1038/s41598-017-10785-1 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Zhao, Bei
Cui, Xingye
Ren, Wei
Xu, Feng
Liu, Ming
Ye, Zuo-Guang
A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating
title A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating
title_full A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating
title_fullStr A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating
title_full_unstemmed A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating
title_short A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating
title_sort controllable and integrated pump-enabled microfluidic chip and its application in droplets generating
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596006/
https://www.ncbi.nlm.nih.gov/pubmed/28900226
http://dx.doi.org/10.1038/s41598-017-10785-1
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