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A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating
A microfluidic chip with a controllable and integrated piezoelectric pump was proposed and demonstrated, where the pump was designed as a micro-actuator based on polyvinylidene fluoride (PVDF) organic piezoelectric film. In this case, the pump should integrate with the microfluidics device very well...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596006/ https://www.ncbi.nlm.nih.gov/pubmed/28900226 http://dx.doi.org/10.1038/s41598-017-10785-1 |
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author | Zhao, Bei Cui, Xingye Ren, Wei Xu, Feng Liu, Ming Ye, Zuo-Guang |
author_facet | Zhao, Bei Cui, Xingye Ren, Wei Xu, Feng Liu, Ming Ye, Zuo-Guang |
author_sort | Zhao, Bei |
collection | PubMed |
description | A microfluidic chip with a controllable and integrated piezoelectric pump was proposed and demonstrated, where the pump was designed as a micro-actuator based on polyvinylidene fluoride (PVDF) organic piezoelectric film. In this case, the pump should integrate with the microfluidics device very well into one chip. The flow rate can be precisely controlled in the range of 0–300 µl/min for water by tuning the V(pp) and frequency of Alternating Current (AC) voltage applied on the diaphragm. To analyze the relationship between the flow rate and the deflection of diaphragm, the deformations of diaphragm at different voltages were researched. The displacement of diaphragm was defined as 17.2 µm at the voltages of 3.5 kV, 5 Hz when the pump chamber was full of water. We have used the integrated microfluidic chip with two pumps for droplet generation to demonstrate its great potential for application in droplet-based microfluidic chip. |
format | Online Article Text |
id | pubmed-5596006 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-55960062017-09-15 A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating Zhao, Bei Cui, Xingye Ren, Wei Xu, Feng Liu, Ming Ye, Zuo-Guang Sci Rep Article A microfluidic chip with a controllable and integrated piezoelectric pump was proposed and demonstrated, where the pump was designed as a micro-actuator based on polyvinylidene fluoride (PVDF) organic piezoelectric film. In this case, the pump should integrate with the microfluidics device very well into one chip. The flow rate can be precisely controlled in the range of 0–300 µl/min for water by tuning the V(pp) and frequency of Alternating Current (AC) voltage applied on the diaphragm. To analyze the relationship between the flow rate and the deflection of diaphragm, the deformations of diaphragm at different voltages were researched. The displacement of diaphragm was defined as 17.2 µm at the voltages of 3.5 kV, 5 Hz when the pump chamber was full of water. We have used the integrated microfluidic chip with two pumps for droplet generation to demonstrate its great potential for application in droplet-based microfluidic chip. Nature Publishing Group UK 2017-09-12 /pmc/articles/PMC5596006/ /pubmed/28900226 http://dx.doi.org/10.1038/s41598-017-10785-1 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Zhao, Bei Cui, Xingye Ren, Wei Xu, Feng Liu, Ming Ye, Zuo-Guang A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating |
title | A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating |
title_full | A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating |
title_fullStr | A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating |
title_full_unstemmed | A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating |
title_short | A Controllable and Integrated Pump-enabled Microfluidic Chip and Its Application in Droplets Generating |
title_sort | controllable and integrated pump-enabled microfluidic chip and its application in droplets generating |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596006/ https://www.ncbi.nlm.nih.gov/pubmed/28900226 http://dx.doi.org/10.1038/s41598-017-10785-1 |
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