Triplebody Mediates Increased Anti-Leukemic Reactivity of IL-2 Activated Donor Natural Killer (NK) Cells and Impairs Viability of Their CD33-Expressing NK Subset

Natural killer cells (NK) are essential for the elimination of resistant acute myeloid and acute lymphoblastic leukemia (AML and ALL) cells. NK cell-based immunotherapies have already successfully entered for clinical trials, but limitations due to immune escape mechanisms were identified. Therefore...

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Detalles Bibliográficos
Autores principales: Kloess, Stephan, Ede Valverde da Silva, Alessa, Oberschmidt, Olaf, Gardlowski, Tanja, Matthies, Nadine, Vyas, Maulik, Arseniev, Lubomir, Heuser, Michael, Pogge von Strandmann, Elke, Köhl, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596090/
https://www.ncbi.nlm.nih.gov/pubmed/28943878
http://dx.doi.org/10.3389/fimmu.2017.01100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596090/
https://www.ncbi.nlm.nih.gov/pubmed/28943878
http://dx.doi.org/10.3389/fimmu.2017.01100

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