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Arginase-II Deficiency Extends Lifespan in Mice

The mitochondrial arginase type II (Arg-II) has been shown to interact with ribosomal protein S6 kinase 1 (S6K1) and mitochondrial p66(Shc) and to promote cell senescence, apoptosis and inflammation under pathological conditions. However, the impact of Arg-II on organismal lifespan is not known. In...

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Detalles Bibliográficos
Autores principales:	Xiong, Yuyan, Yepuri, Gautham, Montani, Jean-Pierre, Ming, Xiu-Fen, Yang, Zhihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596098/ https://www.ncbi.nlm.nih.gov/pubmed/28943853 http://dx.doi.org/10.3389/fphys.2017.00682

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