Metabolic Stress-Induced Activation of AMPK and Inhibition of Constitutive Phosphoproteins Controlling Smooth Muscle Contraction: Evidence for Smooth Muscle Fatigue?

Metabolic stress diminishes smooth muscle contractile strength by a poorly defined mechanism. To test the hypothesis that metabolic stress activates a compensatory cell signaling program to reversibly downregulate contraction, arterial rings and bladder muscle strips in vitro were deprived of O(2) a...

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Detalles Bibliográficos
Autores principales: Smith, Corey A., Miner, Amy S., Barbee, Robert W., Ratz, Paul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596101/
https://www.ncbi.nlm.nih.gov/pubmed/28943852
http://dx.doi.org/10.3389/fphys.2017.00681

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