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Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling

Coronary artery disease (CAD) is a critical cardiovascular disease and a cause of high morbidity and mortality in this world. Hyperhomocysteinemia (HHcy) has been suggested as a risk factor for CAD. In addition, SIRT1 (sirtuin 1) has been reported to play a protective role in a variety of diseases,...

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Detalles Bibliográficos
Autores principales: Chan, Shih-Hung, Hung, Ching-Hsia, Shih, Jhih-Yuan, Chu, Pei-Ming, Cheng, Yung-Hsin, Lin, Huei-Chen, Hsieh, Pei-Ling, Tsai, Kun-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596261/
https://www.ncbi.nlm.nih.gov/pubmed/28888894
http://dx.doi.org/10.1016/j.redox.2017.08.016