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Role of glutathione biosynthesis in endothelial dysfunction and fibrosis

Glutathione (GSH) biosynthesis is essential for cellular redox homeostasis and antioxidant defense. The rate-limiting step requires glutamate-cysteine ligase (GCL), which is composed of the catalytic (GCLc) and the modulatory (GCLm) subunits. To evaluate the contribution of GCLc to endothelial funct...

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Detalles Bibliográficos
Autores principales:	Espinosa-Díez, Cristina, Miguel, Verónica, Vallejo, Susana, Sánchez, Francisco J., Sandoval, Elena, Blanco, Eva, Cannata, Pablo, Peiró, Concepción, Sánchez-Ferrer, Carlos F., Lamas, Santiago
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596265/ https://www.ncbi.nlm.nih.gov/pubmed/28888203 http://dx.doi.org/10.1016/j.redox.2017.08.019

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