Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission

A 58-year-old man with a recent history of generalized myalgia and muscle weakness was transferred to our hospital because of acute progressive dyspnea. The patient underwent left ventricular (LV) assist device (LVAD) implantation due to cardiogenic shock with a LV ejection fraction (LVEF) of 6%. Th...

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Autores principales: Ooka, Junichi, Tanaka, Hidekazu, Hatani, Yutaka, Tsuji, Yukio, Takeshige, Ryo, Mori, Shumpei, Matsumoto, Kensuke, Hara, Shigeo, Tanaka, Hiroshi, Okita, Yutaka, Hirata, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596276/
https://www.ncbi.nlm.nih.gov/pubmed/28781324
http://dx.doi.org/10.2169/internalmedicine.8639-16
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author Ooka, Junichi
Tanaka, Hidekazu
Hatani, Yutaka
Tsuji, Yukio
Takeshige, Ryo
Mori, Shumpei
Matsumoto, Kensuke
Hara, Shigeo
Tanaka, Hiroshi
Okita, Yutaka
Hirata, Ken-ichi
author_facet Ooka, Junichi
Tanaka, Hidekazu
Hatani, Yutaka
Tsuji, Yukio
Takeshige, Ryo
Mori, Shumpei
Matsumoto, Kensuke
Hara, Shigeo
Tanaka, Hiroshi
Okita, Yutaka
Hirata, Ken-ichi
author_sort Ooka, Junichi
collection PubMed
description A 58-year-old man with a recent history of generalized myalgia and muscle weakness was transferred to our hospital because of acute progressive dyspnea. The patient underwent left ventricular (LV) assist device (LVAD) implantation due to cardiogenic shock with a LV ejection fraction (LVEF) of 6%. The histological findings obtained from LV apex showed the infiltration of multinucleated giant cells and severe myocardial contusion. Combining this histological finding with our experienced neurologists comments, resulted in a final diagnosis of fulminant giant cell myocarditis associated with polymyositis. A day after LVAD implantation, the patient received corticosteroid and immunosuppressive therapy, and the LVEF recovered to 68%.
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spelling pubmed-55962762017-09-14 Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission Ooka, Junichi Tanaka, Hidekazu Hatani, Yutaka Tsuji, Yukio Takeshige, Ryo Mori, Shumpei Matsumoto, Kensuke Hara, Shigeo Tanaka, Hiroshi Okita, Yutaka Hirata, Ken-ichi Intern Med Case Report A 58-year-old man with a recent history of generalized myalgia and muscle weakness was transferred to our hospital because of acute progressive dyspnea. The patient underwent left ventricular (LV) assist device (LVAD) implantation due to cardiogenic shock with a LV ejection fraction (LVEF) of 6%. The histological findings obtained from LV apex showed the infiltration of multinucleated giant cells and severe myocardial contusion. Combining this histological finding with our experienced neurologists comments, resulted in a final diagnosis of fulminant giant cell myocarditis associated with polymyositis. A day after LVAD implantation, the patient received corticosteroid and immunosuppressive therapy, and the LVEF recovered to 68%. The Japanese Society of Internal Medicine 2017-08-01 2017-08-15 /pmc/articles/PMC5596276/ /pubmed/28781324 http://dx.doi.org/10.2169/internalmedicine.8639-16 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ooka, Junichi
Tanaka, Hidekazu
Hatani, Yutaka
Tsuji, Yukio
Takeshige, Ryo
Mori, Shumpei
Matsumoto, Kensuke
Hara, Shigeo
Tanaka, Hiroshi
Okita, Yutaka
Hirata, Ken-ichi
Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission
title Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission
title_full Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission
title_fullStr Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission
title_full_unstemmed Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission
title_short Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission
title_sort treatment of fulminant giant cell myocarditis associated with polymyositis using a left ventricular assist device and subsequent corticosteroid and immunosuppressive therapy leading to remission
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596276/
https://www.ncbi.nlm.nih.gov/pubmed/28781324
http://dx.doi.org/10.2169/internalmedicine.8639-16
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