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Towards a systematic assessment of assay interference: Identification of extensively tested compounds with high assay promiscuity
A large-scale statistical analysis of hit rates of extensively assayed compounds is presented to provide a basis for a further assessment of assay interference potential and multi-target activities. A special feature of this investigation has been the inclusion of compound series information in acti...
Autores principales: | Gilberg, Erik, Stumpfe, Dagmar, Bajorath, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596351/ https://www.ncbi.nlm.nih.gov/pubmed/28928939 http://dx.doi.org/10.12688/f1000research.12370.2 |
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