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Blocking endothelin-1-receptor/β-catenin circuit sensitizes to chemotherapy in colorectal cancer

The limited clinical response to conventional chemotherapeutics observed in colorectal cancer (CRC) may be related to the connections between the hyperactivated β-catenin signaling and other pathways in CRC stem-like cells (CRC-SC). Here, we show the mechanistic link between the endothelin-1 (ET-1)/...

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Detalles Bibliográficos
Autores principales:	Cianfrocca, Roberta, Rosanò, Laura, Tocci, Piera, Sestito, Rosanna, Caprara, Valentina, Di Castro, Valeriana, De Maria, Ruggero, Bagnato, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596423/ https://www.ncbi.nlm.nih.gov/pubmed/28708138 http://dx.doi.org/10.1038/cdd.2017.121

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