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p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure

Hypertension-induced cardiac hypertrophy and attenuated cardiac function are the major characteristics of early stage heart failure. Cardiomyocyte death in pathological cardiac conditions is the primary cause of heart failure and mortality. Our previous studies found that heat shock factor 1 (HSF1)...

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Detalles Bibliográficos
Autores principales:	Huang, Chih-Yang, Pai, Pei-Ying, Kuo, Chia-Hua, Ho, Tsung-Jung, Lin, Jing-Ying, Lin, Ding-Yu, Tsai, Fu-Jen, Padma, V Vijaya, Kuo, Wei-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596536/ https://www.ncbi.nlm.nih.gov/pubmed/28796250 http://dx.doi.org/10.1038/cddis.2017.320

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