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Differential spatial expression of peripheral olfactory neuron-derived BACE1 induces olfactory impairment by region-specific accumulation of β-amyloid oligomer

Olfactory dysfunction is a common symptom associated with neurodegenerative diseases including Alzheimer’s disease (AD). Although evidence exists to suggest that peripheral olfactory organs are involved in the olfactory dysfunction that accompanies AD pathology, the underlying mechanisms are not ful...

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Detalles Bibliográficos
Autores principales: Yoo, Seung-Jun, Lee, Ji-Hye, Kim, So Yeun, Son, Gowoon, Kim, Jae Yeon, Cho, Bongki, Yu, Seong-Woon, Chang, Keun-A, Suh, Yoo-Hun, Moon, Cheil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596540/
https://www.ncbi.nlm.nih.gov/pubmed/28796251
http://dx.doi.org/10.1038/cddis.2017.349

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