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Differential spatial expression of peripheral olfactory neuron-derived BACE1 induces olfactory impairment by region-specific accumulation of β-amyloid oligomer
Olfactory dysfunction is a common symptom associated with neurodegenerative diseases including Alzheimer’s disease (AD). Although evidence exists to suggest that peripheral olfactory organs are involved in the olfactory dysfunction that accompanies AD pathology, the underlying mechanisms are not ful...
Autores principales: | Yoo, Seung-Jun, Lee, Ji-Hye, Kim, So Yeun, Son, Gowoon, Kim, Jae Yeon, Cho, Bongki, Yu, Seong-Woon, Chang, Keun-A, Suh, Yoo-Hun, Moon, Cheil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596540/ https://www.ncbi.nlm.nih.gov/pubmed/28796251 http://dx.doi.org/10.1038/cddis.2017.349 |
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