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p53-R273H upregulates neuropilin-2 to promote cell mobility and tumor metastasis

Mounting evidence indicates that hotspot p53 mutant proteins often possess gain-of-function property in promoting cell mobility and tumor metastasis. However, the molecular mechanisms are not totally understood. In this study, we demonstrate that the hotspot mutation, p53-R273H, promotes cell migrat...

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Detalles Bibliográficos
Autores principales:	Lv, Tao, Wu, Xianqiang, Sun, Lijuan, Hu, Qingyong, Wan, Yang, Wang, Liang, Zhao, Zhiqiang, Tu, Xiao, Xiao, Zhi-Xiong Jim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596564/ https://www.ncbi.nlm.nih.gov/pubmed/28796261 http://dx.doi.org/10.1038/cddis.2017.376

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