Cargando…
Total tanshinones exhibits anti-inflammatory effects through blocking TLR4 dimerization via the MyD88 pathway
Tanshinones belong to a group of lipophilic constituents of Salvia miltiorrhiza Bunge (Danshen), which is widely used in traditional Chinese medicine. A deluge of studies demonstrated that tanshinones exert anti-inflammatory effects, but the underlying mechanisms remain unclear to date. This study i...
Autores principales: | Gao, Hongwei, Liu, Xin, Sun, Wen, Kang, Naixin, Liu, Yanli, Yang, Shilin, Xu, Qiong-ming, Wang, Chunming, Chen, Xiuping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596575/ https://www.ncbi.nlm.nih.gov/pubmed/28817116 http://dx.doi.org/10.1038/cddis.2017.389 |
Ejemplares similares
-
Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020) -
MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
por: Block, Matthew S., et al.
Publicado: (2018) -
Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis
por: Zheng, Chao, et al.
Publicado: (2020) -
Diethyl Blechnic Exhibits Anti-Inflammatory and Antioxidative Activity via the TLR4/MyD88 Signaling Pathway in LPS-Stimulated RAW264.7 Cells
por: He, Jia, et al.
Publicado: (2019) -
Tanshinone IIA reduces pyroptosis in rats with coronary microembolization by inhibiting the TLR4/MyD88/NF-κB/NLRP3 pathway
por: Li, Hao-Liang, et al.
Publicado: (2022)