Lytic cell death induced by melittin bypasses pyroptosis but induces NLRP3 inflammasome activation and IL-1β release

The nucleotide-binding domain and leucine-rich repeat-containing receptor with a pyrin domain 3 (NLRP3) inflammasome is a sensor for different types of infections and alterations of homeostatic parameters, including abnormally high levels of the extracellular nucleotide ATP or crystallization of dif...

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Detalles Bibliográficos
Autores principales: Martín-Sánchez, Fátima, Martínez-García, Juan José, Muñoz-García, María, Martínez-Villanueva, Miriam, Noguera-Velasco, José A, Andreu, David, Rivas, Luís, Pelegrín, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596576/
https://www.ncbi.nlm.nih.gov/pubmed/28796264
http://dx.doi.org/10.1038/cddis.2017.390

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