Amlexanox, a selective inhibitor of IKBKE, generates anti-tumoral effects by disrupting the Hippo pathway in human glioblastoma cell lines

Glioblastoma multiforme (GBM) is the most prevalent form of malignant brain tumor. Amlexanox, a novel compound, has been shown to have anti-cancer potential. In this study, the anti-tumoral effects and the underlying mechanisms of amlexanox were investigated. Amlexanox significantly suppressed proli...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Lu, Jie, Zhang, Zhimeng, Zhu, Lin, Dong, Shicai, Guo, Gaochao, Li, Ruohong, Nan, Yang, Yu, Kai, Zhong, Yue, Huang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596579/
https://www.ncbi.nlm.nih.gov/pubmed/29048430
http://dx.doi.org/10.1038/cddis.2017.396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596579/
https://www.ncbi.nlm.nih.gov/pubmed/29048430
http://dx.doi.org/10.1038/cddis.2017.396

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